Sildigra 250 mg tablet is a high-strength oral medication used to treat erectile dysfunction (ED) in adult men. It contains 250 mg of sildenafil citrate and is intended for individuals who require a stronger pharmacological response to achieve and maintain an erection suitable for sexual activity.
| Active Ingredient | Sildenafil Citrate |
| Brand/Strength | Sildigra 250mg |
| Drug Class | Phosphodiesterase Type 5 (PDE 5) Inhibitors |
| Manufacturer | RSM Multilink LLP |
| Common Uses | Treats erectile dysfunction (ED) |
What is Sildigra 250mg?
Sildigra 250 belongs to the PDE5 inhibitor class of medications. Manufactured by RSM Multilink LLP, it serves as a high-strength alternative to standard Sildenafil doses. Each tablet is formulated to improve the physiological response to sexual stimulation by optimizing blood flow to the penile tissues.
Fast Facts:
Manufacturer: RSM Multilink LLP
Active Component: Sildenafil Citrate
Dosage Strength: 250mg (Extra Strength)
Onset of Action: 30–60 minutes
Duration of Effect: 4–6 hours
How It Works
Sildigra 250 functions by targeting the biological enzymes responsible for blood flow regulation.
- Enzyme Inhibition: It blocks the Phosphodiesterase Type 5 (PDE5) enzyme.
- cGMP Elevation: By inhibiting PDE5, the levels of cyclic Guanosine Monophosphate (cGMP) increase.
- Vasodilation: This process relaxes the smooth muscles in the penile blood vessels, allowing for increased arterial blood inflow.
- Erection Maintenance: The result is a firm erection that can be maintained during sexual intercourse.
Important: Sildigra is not an aphrodisiac; it requires natural sexual arousal to be effective.
Administration and Dosage Guidelines
For maximum efficacy and safety, Sildigra 250 must be used according to professional medical advice:
- Timing: Administer one tablet 30 to 60 minutes before anticipated sexual activity.
- Method: Swallow the tablet whole with water. Do not crush or chew the medication, as this can interfere with the absorption rate.
- Dietary Considerations: You may take it with or without food. However, avoiding high-fat meals is recommended, as fats can delay the medication’s onset.
- Frequency: Strict limit of one tablet per 24-hour period.
Safety Profile and Potential Side Effects
While Sildigra 250 is effective, its high concentration makes it vital to monitor for adverse reactions.
Common Adverse Effects
Most side effects are temporary and mild, including:
- Facial flushing or warmth
- Headaches and dizziness
- Nasal congestion
- Indigestion or mild stomach upset
Serious Warnings
Consult a physician immediately if you experience:
- Priapism: An erection lasting more than 4 hours.
- Vision Loss: Sudden changes or blurring of vision.
- Hearing Impairment: Sudden decrease or loss of hearing.
Contraindications
- Nitrates: Never combine with nitrate-based medications (often for chest pain) as it causes dangerous blood pressure drops.
- Alcohol & Grapefruit: Avoid excessive alcohol and grapefruit juice, as both can increase the risk of severe side effects.
- Pre-existing Conditions: Use with caution if you have liver disease, severe kidney impairment, or cardiovascular issues.
FAQs
Is Sildigra 250mg safe for a first-time user?
No. Medical professionals strongly advise against starting with a 250mg dose. Beginners are typically prescribed 50mg. Jumping straight to 250mg without established tolerance can lead to severe adverse effects, including fainting, vomiting, and dangerous heart palpitations.
Why is Sildigra 250mg popular despite the high dosage?
This strength is often sought after as a “last-resort” oral treatment. It is popular among men for whom standard doses (50mg or 100mg) have lost effectiveness. It offers a non-invasive alternative for those facing the possibility of penile implants or injections.
Can I split or cut a Sildigra 250mg tablet?
While tablets are ideally swallowed whole, many users cut the 250mg pill into halves or quarters. This allows for customized dosing (such as two 125mg doses), making it a highly cost-effective option for long-term management of ED.
Is Sildigra 250mg FDA approved?
Sildenafil Citrate (the active ingredient) is FDA-approved. However, the specific 250mg concentration is a generic innovation manufactured in facilities (primarily in India) that follow international standards. Note that 250mg exceeds the standard 100mg maximum typically recommended by the FDA, so it is used “off-label” for high-resistance cases.
How long do the effects of Sildigra 250mg last?
While peak performance usually spans 6 to 8 hours, the high concentration of Sildenafil can remain in your system for over 24 hours. Because of this long half-life, you must never exceed one dose in a 24-hour period to avoid toxicity.
Will Sildigra 250mg increase my size?
Sildigra does not permanently change your anatomy. However, by maximizing blood flow to the absolute limit, an erection may appear fuller and have more girth compared to a partial or weak erection.
Should I take Sildigra 250mg with food or on an empty stomach?
For the fastest absorption, it is best taken on an empty stomach or after a light snack. A heavy, high-fat meal can act as a barrier, significantly delaying the time it takes for the medication to enter your bloodstream.
Does Sildigra 250mg assist with recovery after prostate surgery?
Yes. High-dose Sildenafil is frequently used in “Penile Rehabilitation” protocols following a prostatectomy. Under medical supervision, it helps maintain blood flow to the tissues to prevent atrophy (shrinkage) during the post-surgical healing phase.
How can I manage a headache after taking this medication?
Headaches are a common side effect of high-dose Sildenafil due to vasodilation. Staying hydrated by drinking plenty of water is the best first step. You should consult your doctor about taking a mild over-the-counter pain reliever like Paracetamol if the discomfort persists.
How do I know if my Sildigra 250mg is genuine?
Authentic Sildigra contains high-purity Sildenafil Citrate. To ensure you are receiving a legitimate product and not a counterfeit, always purchase from reputable and verified suppliers.
Is Sildigra 250 safe for everyone?
No. This is a high-strength dose. Men with heart conditions, blood pressure instability, or those taking alpha-blockers must consult a doctor before use.
Can I take Sildigra 250 every day?
It is intended for use as needed. Daily use of such a high dosage is generally not recommended without specific medical supervision.
What should I do if I miss a dose?
Since Sildigra is taken only before sexual activity, there is no set schedule. If you miss a planned dose, simply take it when needed next, ensuring you do not exceed the daily limit.

